Predict whether or not the right drug and dose is given to the individual
Pharmacogenomics is transforming the practice of medicine by providing clinicians with the tools to predict whether a medication will be effective and safe for a particular person and to help prevent adverse drug reactions. There are now gene tests available that guide the dose and selection of approximately 50% of drugs in clinical practice and this testing is called pharmacogenomic testing.
The following case studies for Depression, Pain Medications, Cardiovascular Disease and Multiple Medications highlight the importance of this test. Click here to read more.
Currently medications are prescribed on a "one size fits all" approach, but they don't work the same way for everyone. It can be difficult to predict who will benefit from a medication, who will not respond at all, and who will experience negative side effects. Of these patients, some will respond as expected to the treatment without side-effects, some will have minimal or sub therapeutic response and some will experience significant side-effects that would result in ceasing of the medication.
The one size fits all approach depicted in the diagram below (Before) assumes that all patients process medications in the same way. In fact pharmacogenomics shows the significant variability amongst individuals in the general population (After). This clearly shows that Pharmacogenomics can identify how different individuals will respond to the same drug.
Figure 1 - Not all medications work the same for all people